2nd Time Around
My 2000 Xterra has 204,000 miles. I changed the plugs at 104,000 miles about five years ago and had the most problems with the #4 plug. This time, at 204,000 miles, I had a lot of problems with #6 and #4. Getting #6 out is not difficult if you can find the right combo of extensions and universal joints. I used a Husky 5/8" socket, a 3" extension, a universal joint, and then a 10" extension. The boot wasn't a problem and the plug came off easily although my left hand got scratched up pretty bad. The hardest part about changing number 6 was getting the new plug thread started correctly. I could find the hole OK but I had a really difficult time trying to turn the plug once you stand it in the hole since you can't get your fingers around it. I didn't want to use the extension/universal joint to start the threads because of the danger of cross-threading it. I persisted by standing the plug in the hole and trying to spin it by "pushing" lightly with one finger on the side of the porcelain part. After about ten tries, I was finally able to get the thread started about an eight of a turn. That was enough for me to put the socket/extensions/universal joint on it and start turning the combo with the socket wrench. The #6 plug went in fine but it ended up taking me about an hour for just that one plug.
I read some of the posts here where some people skipped the #6 plug and did a five plug change only. Not a good idea! That plug will eventually fail. My second set of plugs (the ones I changed this time at 204,000 miles) lasted about 100,000 miles. My first set lasted about 104,000 miles. I was going to wait until I got to 208,000 miles before changing the plugs this time, but I got a flashing "check engine light" at 204,000 with a P302 code (2nd cylinder misfire). Fortunately it happened when I started the car at home one morning. A steadily flashing check engine light with cylinder misfire code means that you can destroy your three-way catalytic converter if you drive with the misfire. A regular (non-flashing) check engine light with a cylinder misfire code is OK to drive with and supposedly won't harm your cat converter.
One last thing, (I mentioned this in a different thread) the #4 plug was really difficult to remove this time. The socket wouldn't go all the way down the shaft to grip the plug. The shaft seems to get narrower as you go down further towards the plug. I remember the first time I changed the plugs at 104,000 miles I had the same problem. I allowed the engine to cool down completely and then the socket fit all the way down the shaft. This time that didn't work and I ended up having to file and sand about .04 inches around the socket to make it fit. This worked perfectly and the plug came off easily after I "shrunk" down the outer diameter of the Husky socket. The Husky socket started out with about a .865" outer diameter. After filing and sanding, it was .825 outer diameter. Checked it with a caliper before and after.
Good luck!